Cargando…

Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction

During pancreas development, endocrine precursors and their progeny differentiate, migrate, and cluster to form nascent islets. The transcription factor Neurogenin 3 (Neurog3) is required for islet development in mice, but its role in these dynamic morphogenetic steps has been inferred from fixed ti...

Descripción completa

Detalles Bibliográficos
Autores principales: Pauerstein, Philip T., Sugiyama, Takuya, Stanley, Susan E., McLean, Graeme W., Wang, Jing, Martín, Martín G., Kim, Seung K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512220/
https://www.ncbi.nlm.nih.gov/pubmed/25901096
http://dx.doi.org/10.2337/db15-0042