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G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro

[Image: see text] G protein-coupled receptor kinases (GRKs) play an important role in the desensitization of G protein-mediated signaling of G protein-coupled receptors (GPCRs). The level of interest in mapping their phosphorylation sites has increased because recent studies suggest that the differe...

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Detalles Bibliográficos
Autores principales: Inagaki, Sayaka, Ghirlando, Rodolfo, Vishnivetskiy, Sergey A., Homan, Kristoff T., White, Jim F., Tesmer, John J. G., Gurevich, Vsevolod V., Grisshammer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512254/
https://www.ncbi.nlm.nih.gov/pubmed/26120872
http://dx.doi.org/10.1021/acs.biochem.5b00285