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The effect of neuronal conditional knock-out of peroxisome proliferator-activated receptors in the MPTP mouse model of Parkinson’s disease

Activation of peroxisome proliferator-activated receptors (PPARs), namely PPARγ and PPARδ, has been shown to provide neuroprotection in a number of neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease (PD). The observed neuroprotective effects in experimental models of PD have be...

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Detalles Bibliográficos
Autores principales: Mounsey, R.B., Martin, H.L., Nelson, M.C., Evans, R.M., Teismann, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512257/
https://www.ncbi.nlm.nih.gov/pubmed/26028469
http://dx.doi.org/10.1016/j.neuroscience.2015.05.048