A Combination of Screening and Computational Approaches for the Identification of Novel Compounds That Decrease Mast Cell Degranulation

High-content screening of compound libraries poses various challenges in the early steps in drug discovery such as gaining insights into the mode of action of the selected compounds. Here, we addressed these challenges by integrating two biological screens through bioinformatics and computational an...

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Detalles Bibliográficos
Autores principales: McShane, Marisa P., Friedrichson, Tim, Giner, Angelika, Meyenhofer, Felix, Barsacchi, Rico, Bickle, Marc, Zerial, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512528/
https://www.ncbi.nlm.nih.gov/pubmed/25838434
http://dx.doi.org/10.1177/1087057115579613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512528/
https://www.ncbi.nlm.nih.gov/pubmed/25838434
http://dx.doi.org/10.1177/1087057115579613

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