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A Randomized Trial to Compare the Safety, Tolerability, and Effectiveness of 3 Antimalarial Regimens for the Prevention of Malaria in Nigerian Patients With Sickle Cell Disease

BACKGROUND: Malaria prophylaxis is recommended for persons with sickle cell disease (SCD), but the value of this has been questioned. The aim of this study was to find out whether intermittent preventive treatment (IPT) with a fixed-dose combination of mefloquine-artesunate (MQAS) or sulfadoxine-pyr...

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Detalles Bibliográficos
Autores principales: Olaosebikan, Rasaq, Ernest, Kolade, Bojang, Kalifa, Mokuolu, Olugbenga, Rehman, Andrea M., Affara, Muna, Nwakanma, Davis, Kiechel, Jean-René, Ogunkunle, Taofik, Olagunju, Tope, Murtala, Rukayat, Omefe, Peter, Lambe, Tosin, Bello, Surajudeen, Ibrahim, Olayinka, Olorunsola, Benedict, Ojuawo, Ayotade, Greenwood, Brian, Milligan, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512609/
https://www.ncbi.nlm.nih.gov/pubmed/25701866
http://dx.doi.org/10.1093/infdis/jiv093