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Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci(†)

Genetics of gene expression (eQTLs or expression QTLs) has proved an indispensable tool for understanding biological pathways and pathomechanisms of trait-associated SNPs. However, power of most genome-wide eQTL studies is still limited. We performed a large eQTL study in peripheral blood mononuclea...

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Detalles Bibliográficos
Autores principales: Kirsten, Holger, Al-Hasani, Hoor, Holdt, Lesca, Gross, Arnd, Beutner, Frank, Krohn, Knut, Horn, Katrin, Ahnert, Peter, Burkhardt, Ralph, Reiche, Kristin, Hackermüller, Jörg, Löffler, Markus, Teupser, Daniel, Thiery, Joachim, Scholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512630/
https://www.ncbi.nlm.nih.gov/pubmed/26019233
http://dx.doi.org/10.1093/hmg/ddv194