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Histamine 1 Receptor Blockade Enhances Eosinophil-Mediated Clearance of Adult Filarial Worms

Filariae are tissue-invasive nematodes that cause diseases such as elephantiasis and river blindness. The goal of this study was to characterize the role of histamine during Litomosoides sigmodontis infection of BALB/c mice, a murine model of filariasis. Time course studies demonstrated that while e...

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Detalles Bibliográficos
Autores principales: Fox, Ellen Mueller, Morris, Christopher P., Hübner, Marc P., Mitre, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512699/
https://www.ncbi.nlm.nih.gov/pubmed/26204515
http://dx.doi.org/10.1371/journal.pntd.0003932