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Ocular Inserts for Sustained Release of the Angiotensin-Converting Enzyme 2 Activator, Diminazene Aceturate, to Treat Glaucoma in Rats

The aim of this study was to develop and evaluate the effects of chitosan inserts for sustained release of the angiotensin-converting enzyme 2 (ACE2) activator, diminazene aceturate (DIZE), in experimental glaucoma. Monolayer DIZE loaded inserts (D+I) were prepared and characterized through swelling...

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Detalles Bibliográficos
Autores principales: Foureaux, Giselle, Franca, Juçara Ribeiro, Nogueira, José Carlos, Fulgêncio, Gustavo de Oliveira, Ribeiro, Tatiana Gomes, Castilho, Rachel Oliveira, Yoshida, Maria Irene, Fuscaldi, Leonardo Lima, Fernandes, Simone Odília Antunes, Cardoso, Valbert Nascimento, Cronemberger, Sebastião, Faraco, André Augusto Gomes, Ferreira, Anderson José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512709/
https://www.ncbi.nlm.nih.gov/pubmed/26204514
http://dx.doi.org/10.1371/journal.pone.0133149