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Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells

For multiple sclerosis, genome wide association studies and follow up studies have identified susceptibility single nucleotide polymorphisms located in or near CLEC16A at chromosome 16p13.13, encompassing among others CIITA, DEXI and SOCS1 in addition to CLEC16A. These genetic variants are located i...

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Detalles Bibliográficos
Autores principales: Leikfoss, Ingvild S., Keshari, Pankaj K., Gustavsen, Marte W., Bjølgerud, Anja, Brorson, Ina S., Celius, Elisabeth G., Spurkland, Anne, Bos, Steffan D., Harbo, Hanne F., Berge, Tone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512731/
https://www.ncbi.nlm.nih.gov/pubmed/26203907
http://dx.doi.org/10.1371/journal.pone.0132957