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Metabolomics changes in a rat model of obstructive jaundice: mapping to metabolism of amino acids, carbohydrates and lipids as well as oxidative stress

The study examined the global metabolic and some biochemical changes in rats with cholestasis induced by bile duct ligation (BDL). Serum samples were collected in male Wistar rats with BDL (n = 8) and sham surgery (n = 8) at day 3 after surgery for metabolomics analysis using a combination of revers...

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Detalles Bibliográficos
Autores principales: Long, Yue, Dong, Xin, Yuan, Yawei, Huang, Jinqiang, Song, Jiangang, Sun, Yumin, Lu, Zhijie, Yang, Liqun, Yu, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512893/
https://www.ncbi.nlm.nih.gov/pubmed/26236101
http://dx.doi.org/10.3164/jcbn.14-147