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Sepsis protects the myocardium and other organs from subsequent ischaemic/reperfusion injury via a MAPK-dependent mechanism

BACKGROUND: Sepsis has been shown to precondition the intact heart against ischaemia/reperfusion (IR) injury, and prior endotoxin exposure of cells in in vitro models has shown evidence of protection against subsequent simulated ischaemia. Our aim in this study is to validate these findings and furt...

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Detalles Bibliográficos
Autores principales: Walshe, Criona M, Laffey, John G, Kevin, Leo, O’Toole, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513033/
https://www.ncbi.nlm.nih.gov/pubmed/26215802
http://dx.doi.org/10.1186/s40635-014-0035-9