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Interplay between TAp73 Protein and Selected Activator Protein-1 (AP-1) Family Members Promotes AP-1 Target Gene Activation and Cellular Growth

Unlike p53, which is mutated at a high rate in human cancers, its homologue p73 is not mutated but is often overexpressed, suggesting a possible context-dependent role in growth promotion. Previously, we have shown that co-expression of TAp73 with the proto-oncogene c-Jun can augment cellular growth...

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Detalles Bibliográficos
Autores principales: Subramanian, Deepa, Bunjobpol, Wilawan, Sabapathy, Kanaga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513121/
https://www.ncbi.nlm.nih.gov/pubmed/26018080
http://dx.doi.org/10.1074/jbc.M115.636548