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Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions

Neuronal calcium sensor-1 (NCS-1) is the primordial member of the neuronal calcium sensor family of EF-hand Ca(2+)-binding proteins. It interacts with both the G-protein-coupled receptor (GPCR) dopamine D2 receptor (D2R), regulating its internalization and surface expression, and the cognate kinases...

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Detalles Bibliográficos
Autores principales: Pandalaneni, Sravan, Karuppiah, Vijaykumar, Saleem, Muhammad, Haynes, Lee P., Burgoyne, Robert D., Mayans, Olga, Derrick, Jeremy P., Lian, Lu-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513130/
https://www.ncbi.nlm.nih.gov/pubmed/25979333
http://dx.doi.org/10.1074/jbc.M114.627059