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Inhibition of Kv1.3 Channels in Human Jurkat T Cells by Xanthohumol and Isoxanthohumol

Using whole-cell patch-clamp technique, we investigated influence of selected compounds from groups of prenylated chalcones and flavonoids: xanthohumol and isoxanthohumol on the activity of Kv1.3 channels in human leukemic Jurkat T cells. Obtained results provide evidence that both examined compound...

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Detalles Bibliográficos
Autores principales: Gąsiorowska, Justyna, Teisseyre, Andrzej, Uryga, Anna, Michalak, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513206/
https://www.ncbi.nlm.nih.gov/pubmed/25688010
http://dx.doi.org/10.1007/s00232-015-9782-0