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Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen
The antiestrogenic drug tamoxifen is widely used in the treatment of estrogen receptor-α-positive breast cancer and substantially decreases recurrence and mortality rates. However, high interindividual variability in response is observed, calling for a personalized approach to tamoxifen treatment. T...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513218/ https://www.ncbi.nlm.nih.gov/pubmed/25940823 http://dx.doi.org/10.1007/s40262-015-0273-3 |