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CCR2 inhibition sequesters multiple subsets of leukocytes in the bone marrow

Chemokine receptor CCR2 mediates monocyte mobilization from the bone marrow (BM) and subsequent migration into target tissues. The degree to which CCR2 is differentially expressed in leukocyte subsets, and the contribution of CCR2 to these leukocyte mobilization from the BM are poorly understood. Us...

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Detalles Bibliográficos
Autores principales: Fujimura, Naoki, Xu, Baohui, Dalman, Jackson, Deng, Hongping, Aoyama, Kohji, Dalman, Ronald L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513281/
https://www.ncbi.nlm.nih.gov/pubmed/26206182
http://dx.doi.org/10.1038/srep11664