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Investigation of purification process stresses on erythropoietin peptide mapping profile
BACKGROUND: Full compliance of recombinant protein peptide mapping chromatogram with the standard reference material, is one of the most basic quality control tests of biopharmaceuticals. Changing a single amino acid substitution or side chain diversity for a given peptide changes protein hydrophobi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513318/ https://www.ncbi.nlm.nih.gov/pubmed/26261816 http://dx.doi.org/10.4103/2277-9175.157836 |