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RE-IIBP Methylates H3K79 and Induces MEIS1-mediated Apoptosis via H2BK120 Ubiquitination by RNF20

Histone lysine methylation contributes to transcriptional regulation by serving as a platform for the recruitment of various cofactors. Intense studies have been conducted for elucidating the functional meaning of H3K79 methylation, and to date, the only known HMTase responsible for the modification...

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Detalles Bibliográficos
Autores principales: Woo Park, Jin, Kim, Kee-Beom, Kim, Ji-Young, Chae, Yun-Cheol, Jeong, Oh-Seok, Seo, Sang-Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513340/
https://www.ncbi.nlm.nih.gov/pubmed/26206755
http://dx.doi.org/10.1038/srep12485