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GSK3β mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway

BACKGROUND: Glycogen synthase kinase-3β (GSK3β) expression and activity are upregulated in pancreatic cancer tissues. In our previous study, we found that stromal cell-derived factor-1/ chemokine receptor C-X-C motif chemokine receptor 4 (SDF-1α/CXCR4) upregulated matrix metalloproteinase 2 (MMP-2)...

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Detalles Bibliográficos
Autores principales: Ying, Xu, Jing, Li, Ma, Shijie, Li, Qianjun, Luo, Xiaoling, Pan, Zhenguo, Feng, Yanling, Feng, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513390/
https://www.ncbi.nlm.nih.gov/pubmed/26213494
http://dx.doi.org/10.1186/s12935-015-0216-y