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Two complementary approaches for intracellular delivery of exogenous enzymes

Intracellular delivery of biologically active proteins remains a formidable challenge in biomedical research. Here we show that biomedically relevant enzymes can be delivered into cells using a new DNA transfection reagent, lipofectamine 3000, allowing assessment of their intracellular functions. We...

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Detalles Bibliográficos
Autores principales: Rust, Aleksander, Hassan, Hazirah H. A., Sedelnikova, Svetlana, Niranjan, Dhevahi, Hautbergue, Guillaume, Abbas, Shaymaa A., Partridge, Lynda, Rice, David, Binz, Thomas, Davletov, Bazbek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513551/
https://www.ncbi.nlm.nih.gov/pubmed/26207613
http://dx.doi.org/10.1038/srep12444