Cargando…
Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue
Sestrin2 is a stress-inducible protein that functions as an antioxidant and inhibitor of mTOR complex 1. In a recent study, we found that Sestrin2 overexpression in brown adipocytes interfered with normal metabolism by reducing mitochondrial respiration through the suppression of uncoupling protein...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513567/ https://www.ncbi.nlm.nih.gov/pubmed/26257706 http://dx.doi.org/10.3389/fendo.2015.00114 |