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Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue

Sestrin2 is a stress-inducible protein that functions as an antioxidant and inhibitor of mTOR complex 1. In a recent study, we found that Sestrin2 overexpression in brown adipocytes interfered with normal metabolism by reducing mitochondrial respiration through the suppression of uncoupling protein...

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Detalles Bibliográficos
Autores principales:	Ro, Seung-Hyun, Semple, Ian, Ho, Allison, Park, Hwan-Woo, Lee, Jun Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513567/ https://www.ncbi.nlm.nih.gov/pubmed/26257706 http://dx.doi.org/10.3389/fendo.2015.00114

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