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Nicotine attenuates the effect of HIV-1 proteins on the neural circuits of working and contextual memories
BACKGROUND: Human immunodeficiency virus (HIV)-1-associated neurocognitive disorders (HAND) are characterized by synaptic damage and neuronal loss in the brain. Excessive glutamatergic transmission and loss of cholinergic neurons are the major indicators of HAND. Nicotine acts as a cholinergic chann...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513611/ https://www.ncbi.nlm.nih.gov/pubmed/26205781 http://dx.doi.org/10.1186/s13041-015-0134-x |