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Nicotine attenuates the effect of HIV-1 proteins on the neural circuits of working and contextual memories

BACKGROUND: Human immunodeficiency virus (HIV)-1-associated neurocognitive disorders (HAND) are characterized by synaptic damage and neuronal loss in the brain. Excessive glutamatergic transmission and loss of cholinergic neurons are the major indicators of HAND. Nicotine acts as a cholinergic chann...

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Detalles Bibliográficos
Autores principales:	Nesil, Tanseli, Cao, Junran, Yang, Zhongli, Chang, Sulie L., Li, Ming D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513611/ https://www.ncbi.nlm.nih.gov/pubmed/26205781 http://dx.doi.org/10.1186/s13041-015-0134-x

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