Donor antigen-primed regulatory T cells permit liver regeneration and phenotype correction in hemophilia A mouse by allogeneic bone marrow stem cells

INTRODUCTION: Cell replacement therapy may be considered as an alternate approach to provide therapeutic dose of plasma factor VIII (FVIII) in patients with hemophilia A (HA). However, immune rejection limits the use of allogeneic cells in this mode of therapy. Here, we have examined the role of don...

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Detalles Bibliográficos
Autores principales: Kochat, Veena, Kanjirakkuzhiyil, Sumod, Baligar, Prakash, Nagarajan, Perumal, Mukhopadhyay, Asok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513683/
https://www.ncbi.nlm.nih.gov/pubmed/26152192
http://dx.doi.org/10.1186/s13287-015-0119-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513683/
https://www.ncbi.nlm.nih.gov/pubmed/26152192
http://dx.doi.org/10.1186/s13287-015-0119-9

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