Cargando…

Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease. It is characterized by neuronal loss and degeneration of the upper motor neurons (UMNs) and lower motor neurons (LMNs), and is usually fatal due to respiratory failure within 3–5 years of onset. Although approxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamashita, Satoshi, Ando, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513711/
https://www.ncbi.nlm.nih.gov/pubmed/26213621
http://dx.doi.org/10.1186/s40035-015-0036-y