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Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease. It is characterized by neuronal loss and degeneration of the upper motor neurons (UMNs) and lower motor neurons (LMNs), and is usually fatal due to respiratory failure within 3–5 years of onset. Although approxi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513711/ https://www.ncbi.nlm.nih.gov/pubmed/26213621 http://dx.doi.org/10.1186/s40035-015-0036-y |