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High-throughput assay and engineering of self-cleaving ribozymes by sequencing

Self-cleaving ribozymes are found in all domains of life and are believed to play important roles in biology. Additionally, self-cleaving ribozymes have been the subject of extensive engineering efforts for applications in synthetic biology. These studies often involve laborious assays of multiple i...

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Detalles Bibliográficos
Autores principales: Kobori, Shungo, Nomura, Yoko, Miu, Anh, Yokobayashi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513843/
https://www.ncbi.nlm.nih.gov/pubmed/25829176
http://dx.doi.org/10.1093/nar/gkv265