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Controlling tetramer formation, subunit rotation and DNA ligation during Hin-catalyzed DNA inversion
Two critical steps controlling serine recombinase activity are the remodeling of dimers into the chemically active synaptic tetramer and the regulation of subunit rotation during DNA exchange. We identify a set of hydrophobic residues within the oligomerization helix that controls these steps by the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513852/ https://www.ncbi.nlm.nih.gov/pubmed/26056171 http://dx.doi.org/10.1093/nar/gkv565 |