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Controlling tetramer formation, subunit rotation and DNA ligation during Hin-catalyzed DNA inversion

Two critical steps controlling serine recombinase activity are the remodeling of dimers into the chemically active synaptic tetramer and the regulation of subunit rotation during DNA exchange. We identify a set of hydrophobic residues within the oligomerization helix that controls these steps by the...

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Detalles Bibliográficos
Autores principales:	Chang, Yong, Johnson, Reid C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513852/ https://www.ncbi.nlm.nih.gov/pubmed/26056171 http://dx.doi.org/10.1093/nar/gkv565

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