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PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex

Polycomb repression complex 2 (PRC2) component EZH2 tri-methylates H3K27 and exerts epigenetic repression on target gene expression. EZH2-mediated epigenetic control of RNA polymerase II (Pol II) transcribed coding gene transcription has been well established. However, little is known about EZH2-med...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Li, Shuai, Dai, Xiaoyan, Ma, Ji, Wan, Junhu, Jiang, Hao, Wang, Peng, Liu, Zhaoli, Zhang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513857/
https://www.ncbi.nlm.nih.gov/pubmed/26038315
http://dx.doi.org/10.1093/nar/gkv574