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RNautophagy/DNautophagy possesses selectivity for RNA/DNA substrates

Lysosomes can degrade various biological macromolecules, including nucleic acids, proteins and lipids. Recently, we identified novel nucleic acid-degradation systems termed RNautophagy/DNautophagy (abbreviated as RDA), in which RNA and DNA are directly taken up by lysosomes in an ATP-dependent manne...

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Detalles Bibliográficos
Autores principales: Hase, Katsunori, Fujiwara, Yuuki, Kikuchi, Hisae, Aizawa, Shu, Hakuno, Fumihiko, Takahashi, Shin-Ichiro, Wada, Keiji, Kabuta, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513860/
https://www.ncbi.nlm.nih.gov/pubmed/26038313
http://dx.doi.org/10.1093/nar/gkv579