Cargando…

The poor homology stringency in the heteroduplex allows strand exchange to incorporate desirable mismatches without sacrificing recognition in vivo

RecA family proteins are responsible for homology search and strand exchange. In bacteria, homology search begins after RecA binds an initiating single-stranded DNA (ssDNA) in the primary DNA-binding site, forming the presynaptic filament. Once the filament is formed, it interrogates double-stranded...

Descripción completa

Detalles Bibliográficos
Autores principales:	Danilowicz, Claudia, Yang, Darren, Kelley, Craig, Prévost, Chantal, Prentiss, Mara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513875/ https://www.ncbi.nlm.nih.gov/pubmed/26089391 http://dx.doi.org/10.1093/nar/gkv610

Ejemplares similares

Single-molecule studies of the stringency factors and rates governing the polymerization of RecA on double-stranded DNA
por: Feinstein, Efraim, et al.
Publicado: (2011)

Complementary strand relocation may play vital roles in RecA-based homology recognition
por: Peacock-Villada, Alexandra, et al.
Publicado: (2012)

The differential extension in dsDNA bound to Rad51 filaments may play important roles in homology recognition and strand exchange
por: Danilowicz, Claudia, et al.
Publicado: (2014)

ATP hydrolysis provides functions that promote rejection of pairings between different copies of long repeated sequences
por: Danilowicz, Claudia, et al.
Publicado: (2017)

RecA homology search is promoted by mechanical stress along the scanned duplex DNA
por: Danilowicz, Claudia, et al.
Publicado: (2012)

CTnDOT integrase performs ordered homology-dependent and homology-independent strand exchanges
por: Malanowska, Karolina, et al.
Publicado: (2007)

Changes in the tension in dsDNA alter the conformation of RecA bound to dsDNA–RecA filaments
por: Conover, Alyson J., et al.
Publicado: (2011)

Homology-dependent interactions determine the order of strand exchange by IntDOT recombinase
por: Laprise, Jennifer, et al.
Publicado: (2010)

RecA requires two molecules of Mg(2+) ions for its optimal strand exchange activity in vitro
por: Kim, Raeyeong, et al.
Publicado: (2018)

A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site
por: Smith, Andrew B., et al.
Publicado: (2006)

A SRS2 homolog from Arabidopsis thaliana disrupts recombinogenic DNA intermediates and facilitates single strand annealing
por: Blanck, Sandra, et al.
Publicado: (2009)

DNA strand displacement, strand annealing and strand swapping by the Drosophila Bloom's syndrome helicase
por: Weinert, Brian T., et al.
Publicado: (2007)

RAD54 controls access to the invading 3′-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae
por: Li, Xuan, et al.
Publicado: (2009)

IS200/IS605 family single-strand transposition: mechanism of IS608 strand transfer
por: He, Susu, et al.
Publicado: (2013)

Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS
por: Monti, Maria Chiara, et al.
Publicado: (2011)

Crystal structure of the Redβ C-terminal domain in complex with λ Exonuclease reveals an unexpected homology with λ Orf and an interaction with Escherichia coli single stranded DNA binding protein
por: Caldwell, Brian J, et al.
Publicado: (2019)

Distinct patterns of Cas9 mismatch tolerance in vitro and in vivo
por: Fu, Becky X.H., et al.
Publicado: (2016)

Kinetics of heterochiral strand displacement from PNA–DNA heteroduplexes
por: Kundu, Nandini, et al.
Publicado: (2021)

Simultaneous binding to the tracking strand, displaced strand and the duplex of a DNA fork enhances unwinding by Dda helicase
por: Aarattuthodiyil, Suja, et al.
Publicado: (2014)

Mismatch discrimination and sequence bias during end-joining by DNA ligases
por: Bilotti, Katharina, et al.
Publicado: (2022)

Switching from single-stranded to double-stranded DNA limits the unwinding processivity of ring-shaped T7 DNA helicase
por: Jeong, Yong-Joo, et al.
Publicado: (2013)

HU binds and folds single-stranded DNA
por: Kamashev, Dmitri, et al.
Publicado: (2008)

Single strand transposition at the host replication fork
por: Lavatine, Laure, et al.
Publicado: (2016)

Mechanism of strand displacement synthesis by DNA replicative polymerases
por: Manosas, Maria, et al.
Publicado: (2012)

Plasmid replication-associated single-strand-specific methyltransferases
por: Fomenkov, Alexey, et al.
Publicado: (2020)

Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors
por: Saydam, Nurten, et al.
Publicado: (2007)

Collaborative coupling between polymerase and helicase for leading-strand synthesis
por: Manosas, Maria, et al.
Publicado: (2012)

Replisome mechanics: lagging strand events that influence speed and processivity
por: Georgescu, Roxana E., et al.
Publicado: (2014)

Molecular basis for DNA strand displacement by NHEJ repair polymerases
por: Bartlett, Edward J., et al.
Publicado: (2016)

Pausing kinetics dominates strand-displacement polymerization by reverse transcriptase
por: Malik, Omri, et al.
Publicado: (2017)

Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences
por: Fajardo-Sanchez, Emmanuel, et al.
Publicado: (2008)

Restriction endonuclease TseI cleaves A:A and T:T mismatches in CAG and CTG repeats
por: Ma, Long, et al.
Publicado: (2013)

A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3′–5′ and 5′–3′ strands by rotating a single active site
por: Sasnauskas, Giedrius, et al.
Publicado: (2010)

Duplex strand joining reactions catalyzed by vaccinia virus DNA polymerase
por: Hamilton, Michael D., et al.
Publicado: (2007)

High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination
por: Yuen, Chaya T L, et al.
Publicado: (2022)

Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands
por: Sanders, Kelly L., et al.
Publicado: (2009)

The Hin recombinase assembles a tetrameric protein swivel that exchanges DNA strands
por: Dhar, Gautam, et al.
Publicado: (2009)

Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA
por: Galletto, Roberto, et al.
Publicado: (2013)

Ring-shaped replicative helicase encircles double-stranded DNA during unwinding
por: Joo, Sihwa, et al.
Publicado: (2019)

A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis
por: Juárez, Raquel, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_u0rd4n709a16hu25jepqv0lsbs