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Induced folding in RNA recognition by Arabidopsis thaliana DCL1

DCL1 is the ribonuclease that carries out miRNA biogenesis in plants. The enzyme has two tandem double stranded RNA binding domains (dsRBDs) in its C-terminus. Here we show that the first of these domains binds precursor RNA fragments when isolated and cooperates with the second domain in the recogn...

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Detalles Bibliográficos
Autores principales: Suarez, Irina P., Burdisso, Paula, Benoit, Matthieu P. M. H., Boisbouvier, Jèrôme, Rasia, Rodolfo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513881/
https://www.ncbi.nlm.nih.gov/pubmed/26101256
http://dx.doi.org/10.1093/nar/gkv627