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Novel lectin-independent approach to detect galactose-deficient IgA1 in IgA nephropathy

BACKGROUND: Galactose-deficient IgA1 (Gd-IgA1) is a critical effector molecule in the pathogenesis of IgA nephropathy (IgAN). Although many researchers have measured serum levels of Gd-IgA1 using snail helix aspersa agglutinin (HAA) lectin-based assay, the lectin-dependent assay has some serious pro...

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Detalles Bibliográficos
Autores principales: Yasutake, Junichi, Suzuki, Yusuke, Suzuki, Hitoshi, Hiura, Naoko, Yanagawa, Hiroyuki, Makita, Yuko, Kaneko, Etsuji, Tomino, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513896/
https://www.ncbi.nlm.nih.gov/pubmed/26109484
http://dx.doi.org/10.1093/ndt/gfv221