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RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression
From the first reported role of the transcription factor RUNX2 in osteoblast and chondrocyte differentiation and migration to its involvement in promigratory/proinvasive behavior of breast, prostate, and thyroid cancer cells, osteosarcoma, or melanoma cells, RUNX2 currently emerges as a key player i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513933/ https://www.ncbi.nlm.nih.gov/pubmed/26204939 http://dx.doi.org/10.1186/s12943-015-0404-3 |