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Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer

BACKGROUND: Ovarian cancer is associated with poor long-term survival due to late diagnosis and development of chemoresistance. Tumour hypoxia is associated with many features of tumour aggressiveness including increased cellular proliferation, inhibition of apoptosis, increased invasion and metasta...

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Detalles Bibliográficos
Autores principales: McEvoy, Lynda M., O’Toole, Sharon A., Spillane, Cathy D., Martin, Cara M., Gallagher, Michael F., Stordal, Britta, Blackshields, Gordon, Sheils, Orla, O’Leary, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513971/
https://www.ncbi.nlm.nih.gov/pubmed/26205780
http://dx.doi.org/10.1186/s12885-015-1539-8