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Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system

Administering vaccines directly to mucosal surfaces can induce both serum and mucosal immune responses. Mucosal responses may prevent establishment of initial infection at the port of entry and subsequent dissemination to other sites. The sublingual route is attractive for mucosal vaccination, but b...

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Detalles Bibliográficos
Autores principales: White, Jessica A, Blum, Jeremy S, Hosken, Nancy A, Marshak, Joshua O, Duncan, Lauren, Zhu, Changcheng, Norton, Elizabeth B, Clements, John D, Koelle, David M, Chen, Dexiang, Weldon, William C, Steven Oberste, M, Lal, Manjari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514067/
https://www.ncbi.nlm.nih.gov/pubmed/25483682
http://dx.doi.org/10.4161/hv.32253