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Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system
Administering vaccines directly to mucosal surfaces can induce both serum and mucosal immune responses. Mucosal responses may prevent establishment of initial infection at the port of entry and subsequent dissemination to other sites. The sublingual route is attractive for mucosal vaccination, but b...
Autores principales: | White, Jessica A, Blum, Jeremy S, Hosken, Nancy A, Marshak, Joshua O, Duncan, Lauren, Zhu, Changcheng, Norton, Elizabeth B, Clements, John D, Koelle, David M, Chen, Dexiang, Weldon, William C, Steven Oberste, M, Lal, Manjari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514067/ https://www.ncbi.nlm.nih.gov/pubmed/25483682 http://dx.doi.org/10.4161/hv.32253 |
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