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PED is overexpressed and mediates TRAIL resistance in human non-small cell lung cancer

PED (phosphoprotein enriched in diabetes) is a death-effector domain (DED) family member with a broad anti-apoptotic action. PED inhibits the assembly of the death-inducing signalling complex (DISC) of death receptors following stimulation. Recently, we reported that the expression of PED is increas...

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Detalles Bibliográficos
Autores principales: Zanca, Ciro, Garofalo, Michela, Quintavalle, Cristina, Romano, Giulia, Acunzo, Mario, Ragno, Pia, Montuori, Nunzia, Incoronato, Mariarosaria, Tornillo, Luigi, Baumhoer, Daniel, Briguori, Carlo, Terracciano, Luigi, Condorelli, Gerolama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514119/
https://www.ncbi.nlm.nih.gov/pubmed/18284607
http://dx.doi.org/10.1111/j.1582-4934.2008.00283.x