Safety and immunogenicity of an investigational 4-component Staphylococcus aureus vaccine with or without AS03(B) adjuvant: Results of a randomized phase I trial

We assessed the safety, reactogenicity and immunogenicity of a staphylococcal vaccine combining capsular polysaccharides types 5 and 8 (CPS5/8), conjugated to tetanus toxoid (TT), with mutated detoxified α-toxin (AT) and clumping factor A (ClfA). In this phase I, randomized, placebo-controlled, obse...

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Detalles Bibliográficos
Autores principales: Levy, Jack, Licini, Laurent, Haelterman, Edwige, Moris, Philippe, Lestrate, Pascal, Damaso, Silvia, Van Belle, Pascale, Boutriau, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514337/
https://www.ncbi.nlm.nih.gov/pubmed/25715157
http://dx.doi.org/10.1080/21645515.2015.1011021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514337/
https://www.ncbi.nlm.nih.gov/pubmed/25715157
http://dx.doi.org/10.1080/21645515.2015.1011021

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