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Safety and immunogenicity of an investigational 4-component Staphylococcus aureus vaccine with or without AS03(B) adjuvant: Results of a randomized phase I trial
We assessed the safety, reactogenicity and immunogenicity of a staphylococcal vaccine combining capsular polysaccharides types 5 and 8 (CPS5/8), conjugated to tetanus toxoid (TT), with mutated detoxified α-toxin (AT) and clumping factor A (ClfA). In this phase I, randomized, placebo-controlled, obse...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514337/ https://www.ncbi.nlm.nih.gov/pubmed/25715157 http://dx.doi.org/10.1080/21645515.2015.1011021 |