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Passive protection of mice against Streptococcus pneumoniae challenge by naturally occurring and vaccine-induced human anti-PhtD antibodies

Currently marketed Streptococcus pneumoniae vaccines are based on polysaccharide capsular antigens from the most common strains. Pneumococcal histidine triad protein D (PhtD) is a conserved surface protein that is being evaluated as a candidate for a vaccine with improved serotype coverage. Here, we...

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Detalles Bibliográficos
Autores principales: Brookes, Roger H, Ming, Marin, Williams, Kimberley, Hopfer, Robert, Gurunathan, Sanjay, Gallichan, Scott, Tang, Mei, Ochs, Martina M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514344/
https://www.ncbi.nlm.nih.gov/pubmed/25912273
http://dx.doi.org/10.1080/21645515.2015.1039210