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A Structural Model of the Human α7 Nicotinic Receptor in an Open Conformation

Nicotinic acetylcholine receptors (nAchRs) are ligand-gated ion channels that regulate chemical transmission at the neuromuscular junction. Structural information is available at low resolution from open and closed forms of an eukaryotic receptor, and at high resolution from other members of the sam...

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Detalles Bibliográficos
Autores principales: Chiodo, Letizia, Malliavin, Thérèse E., Maragliano, Luca, Cottone, Grazia, Ciccotti, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514475/
https://www.ncbi.nlm.nih.gov/pubmed/26208301
http://dx.doi.org/10.1371/journal.pone.0133011