Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity

Numerous studies have shown a paradoxical positive correlation between elevated levels of plasminogen activator inhibitior-1 (PAI-1) in tumors and blood of cancer patients with poor clinical outcome, suggesting that PAI-1 could be a therapeutic target. Here we tested two orally bioavailable small mo...

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Detalles Bibliográficos
Autores principales: Placencio, Veronica R., Ichimura, Atsuhiko, Miyata, Toshio, DeClerck, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514594/
https://www.ncbi.nlm.nih.gov/pubmed/26207899
http://dx.doi.org/10.1371/journal.pone.0133786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514594/
https://www.ncbi.nlm.nih.gov/pubmed/26207899
http://dx.doi.org/10.1371/journal.pone.0133786

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