Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice

BACKGROUND: Various transient receptor potential (TRP) channels in sensory neurons contribute to the transduction of mechanical stimuli in the colon. Recently, even the cold-sensing menthol receptor TRPM(melastatin)8 was suggested to be involved in murine colonic mechano-nociception. METHODS: To ana...

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Detalles Bibliográficos
Autores principales: Mueller-Tribbensee, Sonja M., Karna, Manoj, Khalil, Mohammad, Neurath, Markus F., Reeh, Peter W., Engel, Matthias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514604/
https://www.ncbi.nlm.nih.gov/pubmed/26207981
http://dx.doi.org/10.1371/journal.pone.0128242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514604/
https://www.ncbi.nlm.nih.gov/pubmed/26207981
http://dx.doi.org/10.1371/journal.pone.0128242

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