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BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila

During tumorigenesis, pathways that promote the epithelial-to-mesenchymal transition (EMT) can both facilitate metastasis and endow tumor cells with cancer stem cell properties. To gain a greater understanding of how these properties are interlinked in cancers we used Drosophila epithelial tumor mod...

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Detalles Bibliográficos
Autores principales: Doggett, Karen, Turkel, Nezaket, Willoughby, Lee F., Ellul, Jason, Murray, Michael J., Richardson, Helena E., Brumby, Anthony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514741/
https://www.ncbi.nlm.nih.gov/pubmed/26207831
http://dx.doi.org/10.1371/journal.pone.0132987