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Zic1 Promoter Hypermethylation in Plasma DNA Is a Potential Biomarker for Gastric Cancer and Intraepithelial Neoplasia

Gastric cancer (GC) remains one of the most common digestive cancers worldwide; however, most patients present at an advanced stage at initial diagnosis. Zic1 is a novel candidate tumor suppressor gene that is epigenetically silenced in GC. In this study, we investigated Zic1 promoter methylation in...

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Detalles Bibliográficos
Autores principales: Chen, Xueqin, Lin, Zhenghua, Xue, Meng, Si, Jianmin, Chen, Shujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514771/
https://www.ncbi.nlm.nih.gov/pubmed/26207911
http://dx.doi.org/10.1371/journal.pone.0133906