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Vpx-Independent Lentiviral Transduction and shRNA-Mediated Protein Knock-Down in Monocyte-Derived Dendritic Cells

The function of dendritic cells (DCs) in the immune system is based on their ability to sense and present foreign antigens. Powerful tools to research DC function and to apply in cell-based immunotherapy are either silencing or overexpression of genes achieved by lentiviral transduction. To date, ef...

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Detalles Bibliográficos
Autores principales: Witkowski, Wojciech, Vermeire, Jolien, Landi, Alessia, Naessens, Evelien, Vanderstraeten, Hanne, Nauwynck, Hans, Favoreel, Herman, Verhasselt, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514788/
https://www.ncbi.nlm.nih.gov/pubmed/26208151
http://dx.doi.org/10.1371/journal.pone.0133651