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The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity

Wnt signaling controls various aspects of developmental and cell biology, as well as contributing to certain cancers. Expression of the human Rho family small GTPase Wrch/RhoU is regulated by Wnt signaling, and Wrch and its paralog Chp/RhoV are both implicated in oncogenic transformation and regulat...

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Detalles Bibliográficos
Autores principales: Kidd, Ambrose R., Muñiz-Medina, Vanessa, Der, Channing J., Cox, Adrienne D., Reiner, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514874/
https://www.ncbi.nlm.nih.gov/pubmed/26208319
http://dx.doi.org/10.1371/journal.pone.0133226